Endocrine Abstracts

A 65-year-old man presenting with urinary symptoms was incidentally discovered to have an adrenal mass on imaging. Abdominal computed tomography (CT) revealed a 9.5 x 8 cm heterogenous solid right adrenal tumour with no evidence of metastatic disease. Family history included a brother who died from metastatic carcinoid and another brother who died from metastatic neuroendocrine tumour. The initial differential lay between adrenocortical carcinoma (ACC) or a pheochromocytoma. T...

Fine-needle aspiration biopsy (FNAB) is the tool of choice for evaluating thyroid nodules but there is a significant percentage of insufficient or indeterminate aspirates and falsely reassuring results have been reported in up to 6% of cases.We aimed to examine our experience with FNAB among a large cohort of unselected patients with thyroid nodules.239 consecutive patients (211 women) underwent FNA of a thyroid nodule between July...

A 65-year-old man presenting with urinary symptoms was incidentally discovered to have an adrenal mass. Abdominal computed tomography (CT) revealed a 9.5x8cm heterogenous solid right adrenal tumor with no evidence of metastatic disease. The initial differential lay between adrenocortical carcinoma (ACC) or a phaeochromocytoma. The elevated plasma fractionated normetanephrine at 14439 pmol/l (0-1180), metanephrine 15202 pmol/l (0-510), 3-MT 415 pmol/l (0-180) led to a presumed ...

Primary aldosteronism (PA) is the most common cause of endocrine hypertension. Following biochemical confirmation of aldosterone excess, adrenal venous sampling (AVS) is the gold standard investigation to lateralise the source of aldosterone hypersecretion in patients deemed suitable for potential adrenalectomy. AVS has been performed for all suitable patients with a diagnosis of PA in Beaumont Hospital since implementation of a new protocol involving collaboration between End...

Background: Fine needle aspiration (FNA) is the preferred method for assessing thyroid nodules but concern remains about false negative results. The primary aim of this study was to investigate the malignancy rate in nodules which were initially classified as benign (BTA classification Thy 2). The secondary aim was to look at the distribution of different cytological categories in a large cohort of patients.Methods: We retrospectively examined 719 nodule...

Introduction: TSH-stimulated serum thyroglobulin (Tg) is used as a sensitive marker for the detection of early recurrence or residual disease following treatment for differentiated thyroid cancer (DTC). However, stimulated Tg, using TSH or thyroid hormone withdrawal, is either costly or cumbersome for patients.Aim: To compare the performance of basal T4 suppressed, with stimulated Tg measurement, in the follow up of patients treated for DTC.</...